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Novus Biologicals
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Novus Biologicals
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Proteintech
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Proteintech
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Santa Cruz Biotechnology
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OriGene
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Biorbyt
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ProSci Incorporated
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Novus Biologicals
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Elabscience Biotechnology
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Image Search Results
Journal: Marine Drugs
Article Title: Anti-Inflammatory Effects of Marine-Derived Resorcylic Acid Lactone Derivatives in Ulcerative Colitis via the MAPK/ERK Pathway
doi: 10.3390/md24020069
Figure Lengend Snippet: Compound 4 exhibits potent in vivo anti-inflammatory activity in DSS-induced colitis. ( A ) Schematic diagram of colitis. C57BL/6 mice were given 3% DSS water for 8 days. 5-ASA (100 mg/kg) and compound 4 (10, 20 mg/kg) were administered daily by gavage for 9 consecutive days, and the mice were sacrificed on day 9. ( B ) At the end of the experiment, the representative results of colon length. The weight ( C ) and DAI score ( D ) of mice in each group were recorded daily. ( E ) spleen index of each group. ( F ) Histopathological images of the colon in each group of mice. Scale bar = 100 µm. ( G ) Expression levels of ZO-1, Occludin, and Claudin-1 in colon tissues of each group. ( H – K ) The concentration of LPS, TNF- α , IL-6, and IL-1 β in the serum of each group. The samples were derived from the same experiment, and the blots were processed in parallel. Data represent mean ± SD, ns: not significant; ## p < 0.01 vs. control group; ** p < 0.01 vs. DSS group.
Article Snippet: After blocking with 5% BSA for 2 h, the membranes were incubated at 4 °C overnight with primary antibodies against the following target proteins: β -Actin (CST, #4970), P-ERK (CST, #5726), ERK (CST, #4695), ZO-1 (Affinity, #AF5145),
Techniques: In Vivo, Activity Assay, Expressing, Concentration Assay, Derivative Assay, Control
Journal: Journal of Clinical Biochemistry and Nutrition
Article Title: Tocotrienol improves learning and memory deficit of aged rats
doi: 10.3164/jcbn.15-52
Figure Lengend Snippet: Effect of T-3 on the disruption of BBB component proteins. (a) The expression of claudin-5 in aged and young rats. * p <0.02 vs young control. (b) The expression of occludin in aged and young rats. * p <0.03 vs young control. (c) The expression of JAM in aged and young rats. * p <0.03 vs young control; n = 9 for each group.
Article Snippet: Antibodies: Anti-c-Src (B-12), p-ERK1/2 (Thr 202/Tyr 204) and junctional adhesion molecule-A (JAM-A) (H-80) were purchased from Santa Cruz Biotechnology, Inc. (Heidelberg, Germany);
Techniques: Expressing